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Microtubule Resonance Simulator

🌲 Part of the Brokenbranch Lab — one human and a cluster of AI agents shipping strange software in public. This is one experiment among many; the front door lists them all.

An interactive computational exploration of fractal electromagnetic resonance in biological nanostructures, based on findings by Bandyopadhyay et al. (2020, 2022).

This is NOT peer-reviewed research. It is an exploratory tool for sharpening questions and testing mathematical plausibility.

Status: 🟡 Complete (exploratory tool — not formally validated)

This experiment is finished, not abandoned. It shipped its full result set in one publication and reached its intended scope: 7 hypotheses tested honestly, the falsified ones (H2) reported as falsified, the unvalidated ones (H7, Schumann alignment, p=0.179) reported as not significant. There is no open backlog and no further work planned. If you find it sitting still, that stillness is done, not neglect.

It remains 🟡 (an exploratory toy, not a validated result) by design. It has not formally passed the Brokenbranch Lab validation gate (the "Four Tests" — reproduced, externally checked, pre-registered, and survives adversarial review). Promoting it to 🟢 would require, at minimum:

  • an independent reproduction of the simulator's key results from the published parameters,
  • external review of the physics engines (especially the H5 pitch-angle robustness and H6 stochastic-resonance parameterization),
  • a pre-registered hypothesis set rather than the post-hoc meta-analysis presented here, and
  • adversarial review of the model-tests-model concerns flagged in H3 (scale invariance is tautological as built).

None of those have been done, so the honest label stays 🟡. The value here is the honesty of the negative results, not a validated claim.

Quick Start

  1. Clone the repository
  2. Open index.html in a browser (or deploy to any static host)
  3. No build step, no dependencies, no server required

Structure

File Purpose
index.html Landing page with context, results summary, and explanations
simulator.html The interactive simulator (5 panels + hypothesis lab + meta-analysis)
whitepaper.html Detailed technical methodology and results
sim.js Visualization and UI logic (~85 KB)
physics.js 10 computational engines (~72 KB)
style.css Simulator design system
landing.css Landing page styles
whitepaper.css Whitepaper reading styles

Tech Stack

  • Pure HTML / CSS / JavaScript (no frameworks, no build step)
  • Canvas-based visualizations with requestAnimationFrame
  • Physics engines: RK4 integration, Monte Carlo sampling, Berry phase computation, stochastic resonance analysis, energy budget calculation

Key Results

Hypothesis Verdict Notes
H1: Fractal Coherent Amplification Plausible Regular lattice beats fractal
H2: Chirality Creates Triplets Falsified Helical modes don't cluster
H3: Scale Invariance Consistent Tautological (model tests model)
H4: Temporal Cascade Consistent Expected from oscillator structure
H5: Pitch Angle Optimality Inconclusive Parameter-dependent (55% robust)
H6: Noise-Fueled Resonance Plausible SR present but parameters unconstrained
H7: Schumann Alignment Unvalidated p=0.179, not significant

Meta-analysis: 86.3% overall robustness. Regular lattice beats fractal for amplification. Active oscillation energetically implausible (16x neuron budget).

References

  1. Bandyopadhyay, A. et al. "Fractal, Scale Free Electromagnetic Resonance of a Single Brain Extracted Microtubule Nanowire, a Single Tubulin Protein, and a Single Neuron." Fractal and Fractional, 2020.
  2. Bandyopadhyay, A. "A century-old picture of the nerve impulse is wrong." Communicative & Integrative Biology, 2022.
  3. Berry, M.V. "Quantal Phase Factors Accompanying Adiabatic Changes." Proc. R. Soc. A, 1984.
  4. Gammaitoni, L. et al. "Stochastic Resonance." Reviews of Modern Physics, 1998.
  5. Naaman, R. & Waldeck, D.H. "Chiral-Induced Spin Selectivity Effect." J. Phys. Chem. Lett., 2012.

Built With

Built as a collaboration between human scientific curiosity and Claude Opus 4.6 (Anthropic).

License

MIT License. See LICENSE.

Contributing

See CONTRIBUTING.md for guidelines.

About

Interactive computational exploration of fractal EM resonance in microtubule nanostructures. Pure HTML/JS, no build. 10 physics engines, 7 hypotheses tested, 86.3% meta-robustness. H2 falsified, H7 unvalidated (p=0.179).

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