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HLA_Allele Significance test Clinical Relevance Method Experimental methods Reference Australia_New_South_Wales_Caucasian_(n=134) Australia_Yuendumu_Aborigine_(n=191) Azores_Central_Islands_(n=59) Azores_Oriental_Islands_(n=43) Azores_Terceira_Island_(n=130) Brazil_Puyanawa_(n=150) Brazil_Barra_Mansa_Rio_State_Caucasian_(n=405) Brazil_Belo_Horizonte_Caucasian_(n=95) Brazil_Mixed_(n=108) Brazil_Rio_de_Janeiro_Caucasian_(n=521) Brazil_Rio_de_Janeiro_Parda_(n=170) Brazil_Terena_(n=60) Brazil_Vale_do_Ribeira_Quilombos_(n=144) Bulgaria_(n=55) Canada_Cree_NA-DHS_3_(G)_(n=18) Chile_Mapuche_(n=66) Chile_Santiago_Mixed_(n=70) China_Canton_Han_(n=264) China_North_Han_(n=105) China_Tibet_Region_Tibetan_(n=158) Colombia_Bogotá_Cord_Blood_(n=1463) Colombia_Wayuu_NA-DHS_15_(G)_(n=15) Costa_Rica_Amerindians_(G)_(n=125) Costa_Rica_Central_Valley_Mestizo_(G)_(n=221) Croatia_(n=150) Croatia_pop_4_(n=4000) Cuba_Caucasian_(n=70) Cuba_Mixed_Race_(n=42) Czech_Republic_(n=106) Czech_Republic_NMDR_(n=5099) England_Blood_Donors_of_Mixed_Ethnicity_(n=519) England_North_West_(n=298) Finland_(n=91) Germany_DKMS_-_Austria_minority_(n=1698) Germany_DKMS_-_Bosnia_and_Herzegovina_minority_(n=1028) Germany_DKMS_-_Croatia_minority_(n=2057) Germany_DKMS_-_France_minority_(n=1406) Germany_DKMS_-_German_donors_(n=3456066) Germany_DKMS_-_Greece_minority_(n=1894) Germany_DKMS_-_Italy_minority_(n=1159) Germany_DKMS_-_Netherlands_minority_(n=1374) Germany_DKMS_-_Portugal_minority_(n=1176) Germany_DKMS_-_Romania_minority_(n=1234) Germany_DKMS_-_Spain_minority_(n=1107) Germany_DKMS_-_Turkey_minority_(n=4856) Germany_DKMS_-_United_Kingdom_minority_(n=1043) Germany_pop_6_(n=8862) Germany_pop_8_(n=39689) Greece_pop_6_(n=242) Greece_pop_8_(n=83) Guatemala_Kaqchikel_NA-DHS_8_(G)_(n=19) Hong_Kong_Chinese_(n=569) Hong_Kong_Chinese_BMDR_(n=7595) Hong_Kong_Chinese_HKBMDR_HLA_11_loci_(n=5266) India_Andhra_Pradesh_Golla_(n=111) India_Kerala_Malayalam_speaking_(n=356) India_Tamil_Nadu_(n=2492) Iran_Baloch_(n=100) Ireland_Northern_(n=1000) Israel_Arab_pop_2_(n=12301) Israel_Argentina_Jews_(n=4307) Israel_Ashkenazi_Jews_pop_3_(n=4625) Israel_Ethiopia_Jews_(n=5928) Israel_Georgia_Jews_(n=4471) Israel_Iran_Jews_(n=8153) Israel_Iraq_Jews_(n=13270) Israel_Morocco_Jews_(n=36718) Israel_Poland_Jews_(n=13871) Israel_Tunisia_Jews_(n=9070) Israel_USA_Jews_(n=6058) Israel_USSR_Jews_(n=45681) Italy_pop_5_(n=975) Malaysia_Peninsular_Indian_(n=271) Mexico_Chiapas_Lacandon_Mayans_(n=218) Mexico_Chihuahua_Chihuahua_City_Pop_2_(n=88) Mexico_Chihuahua_Tarahumara_(n=44) Mexico_Guadalajara_Mestizo_pop_2_(n=103) Mexico_Hidalgo_Mezquital_Valley/_Otomi_(n=72) Mexico_Mestizo_(n=41) Mexico_Mexico_City_Mestizo_pop_2_(n=234) Mexico_Mexico_City_Mestizo_population_(n=143) Mexico_Mexico_City_Tlalpan_(n=330) Mexico_Mixtec_(n=97) Mexico_Mixtec_NA-DHS_5_(G)_(n=20) Mexico_Oaxaca_Jamiltepec_Mixtec_(n=96) Mexico_Oaxaca_Mixtec_(n=103) Mexico_Oaxaca_Zapotec_(n=90) Mexico_Veracruz_Xalapa_(n=84) Morocco_Atlantic_Coast_Chaouya_(n=98) Morocco_Nador_Metalsa_pop_2_(n=73) Morocco_Settat_Chaouya_(n=98) Netherlands_Leiden_(n=1305) New_Caledonia_(n=65) New_Zealand_Maori_with_Admixed_History_(n=105) Nicaragua_Managua_(n=339) Nicaragua_Mestizo_(G)_(n=155) Oman_(n=118) Panama_(n=462) Papua_New_Guinea_East_New_Britain_Rabaul_(n=60) Papua_New_Guinea_Eastern_Highlands_Goroka_Asaro_(n=57)
B*39:06 P =0 .006 Secreted higher levels of IL-1β Experimentally proven Neutralizing Antibody Assay, IFN-γ Elispot, Cytokine Measurements, HLA Genotyping https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096794/ 0.011 0 0 0.013 0.008 0.02 0.016 0.007 0.009 0 0.024 0.002 0 0 0.0041 0 0.003 0.014 0 0.00402 0.011 0.00559 0.00097 0.00194 0.00391 0.00523 0.00422 0.00129 0.00485 0.00425 0.00486 0.00497 0.00216 0.00815 0.0055 0.00472 0.012 0.00602 0 7E-05 0.005 0.0006 0.009 0.00061 0.0007 0.00757 0.00034 0.00011 6E-05 8E-05 0.00496 0.00656 0.00017 0.00834 0.00103 0.006 0.00185 0.014 0.0057 0 0.068 0.028 0.021 0.052 0.052 0.088 0.045 0.006 0 0 0.007 0 0.01 0.003 0.025 0.0011 0 0
B*39:06:01 0 0 0.033 0.004 0 0 0.014 0
B*39:06:02 0.00741 0.0019 0.0088 0 0.028 0 0.002 0 0.0087 0.002 0.026 9E-05 0.001 0.01 0.011 0.019 0.05 0.007 0 0.007 0.013
Total Frequency 0.011 0 0 0.013 0.008 0.02 0.007 0.016 0.007 0.002 0.009 0.009 0 0 0.028 0.024 0 0.002 0 0 0.004 0.033 0.004 0.002 0 0.003 0.014 0 0 0.004 0.009 0.002 0.011 0.006 0.001 0.002 0.004 0.005 0.004 0.001 0.005 0.004 0.005 0.005 0.002 0.008 0.006 0.005 0.012 0.006 0.026 0 0 0 0.005 0.001 0.001 0.01 0.009 0.001 0.001 0.008 0 0 0 0 0.005 0.007 0 0.008 0.001 0.006 0.002 0.014 0.006 0.011 0.019 0.014 0 0.068 0.028 0.021 0.052 0.05 0.052 0.088 0.045 0.006 0.007 0 0.007 0.007 0 0.01 0.003 0.013 0.025 0.001 0 0